Brand Lipitor is a very renowned medication, also widely known as Atorvastatin, which is an active component of this drug. This cholesterol medication is an HMG CoA reductase inhibitor drug, which is used in reducing the patient’s blood cholesterol levels. Treatment with this medicine also prevents the production of LDL in the body. This medication also stops the quantity of triglycerides, cholesterol and Apo lipoprotein B.


This medicament also increases the production of good cholesterol and removes the bad cholesterol, which leads to the blockage of artery. It is also used to the treatment of strokes and heart attacks.

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Lipitor is available in various doses like 5mg, 10mg, 20mg and 40 mg.


Atorvastatin shows its therapeutic effects by inhibiting the hepatic enzyme HMG-CoA reductase. The function of HMG-CoA reductase is to convert HMG-CoA to mevalonate in the cholesterol biosynthesis pathway, which leads to a successive reduction in cholesterol levels in the liver. A reduced cholesterol level of liver activates hepatic LDL-C receptors which enhances the hepatic uptake of LDL-C and reduces LDL-C concentrations in the serum.


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Dose of Lipitor


Generic Atorvastatin is consumed one time in a day, with or without foods. You should take this medicine on the regular basis at the same time. Avoid breaking or crushing of this medicine, you should swallow it as whole along with the sufficient amount of water.


• Hyperlipidemia: A patient should consume a prescribed dose of 10 or 20 mg once in a day. Patients who need a large amount of reduction in LDL-C should start with a dose of 40 mg once in a day. The maximum dose of this medication should not exceed more than 40 mg once in a day.


• In case of Hypercholesterolemia: A dose of 10mg should be consumed and a dose should not increase more than 20 mg once in a day.


Contraindications


• If you are allergic to Atorvastatin, then you should avoid intake of this medication as it may lead to various allergic reactions like hives, redness of skin, rashes, swelling of lips, face and eyes.
• Avoid this medication in case of pregnant females and breast feeding mothers.
• Do not take this medicament if you are suffering from hepatic and renal impairment.


Various undesired adverse effects of Lipitor are


Kidney problems: such as difficulty in urination or painful urination, swelling of face, feet and ankles, weakness and shortness of breath.

Liver problems: - nausea, abdominal pain, itching, loss of appetite and dark color urine.


Sudden numbness or weakness come in severe headache and problems with vision or balance.


Points to remember!


• You should not eat food that have high amount of fat because this medicine will not be effective in reducing the cholesterol.
• Avoid drinking of alcoholic beverages along with this medication as it increases the level of triglycerides and may increase the chance of liver damage.
• Intake of Grapefruit and grapefruit juice should be avoided along with this medication as it may interact with this drug and result in very severe side effects.
• You should avoid consumption of prescription, non-prescription drugs and herbal products along with this medicine.


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