Angina pectoris is a chest pain, discomfort, or tightness that occurs when a part of the heart muscles receives a reduced blood oxygen supply. It is the most common type of heart disease.

Angina may be noticeable in the form of an angina attack or pain in the chest that stays from 1 to 15 minutes. The situation is classified by the pattern of attacks such as:


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• Stable angina: It is a chronic type of angina which comes arrives when the heart works harder than usual, such as during exercise. Symptoms are calmed by rest and medicine.
• Unstable angina: This type of attack does not follow regular pattern. It can occur when at rest and is very less common and which is not comforted by rest or medications.
• Variant angina: This type of attack is very rare and can happen at rest. It occurs due to angina contraction or relaxation of the blood vessels leading to the reduced blood flow to the heart.

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Working of Ranexa

Ranexa shows its action by restraining the excess amount of sodium that flows into the heart at the time of angina attack. Presence of sodium inside the heart results in the excess amount of calcium leading to the contraction of heart muscles, thus making them stiff. The inhibition of flow of sodium into the heart leads to less amount of calcium resulting in the reduced tension in the heart wall.

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Prescribed dose of Ranexa

For treatment of angina pectoris, a person should consume an initial dose of 500 mg two times in a day. The maximum dose should not exceed more than 1000mg twice in a day. It can be consumed with or without food. As this medicine is available in the form of extended released tablets, so it should be administered orally along with a glass of water.

Situations in which Ranexa should not be consumed are:


• Avoid consumption of this medicine if you are allergic to generic Ranolazine.
• Pregnant and breast feeding females should avoid use of this medicine.
• Person suffering from hepatic and renal impairment should avoid consumption of this medicine.
• If you are consuming azole antifungal, then you should avoid intake of this medicine.

Side effects are caused due to overdose or due to improper following of dosing schedule. Some of the adverse effects exhibited by Ranexa are nausea, constipation, headache, dizziness, fast or pounding heartbeats, little or no urinating, painful urination, swelling in your feet or ankles, feeling tired and shortness of breath.

Precautionary measures to be followed while using Ranexa are:


• You should avoid consumption of grapefruit or grape juice along with this medicine as it may lead to severe adverse effect.
• Intake of this medicine impairs the thinking of a person and makes you sleepy and lethargic, so you should avoid driving or doing any task that needs full focus.
• Geriatric patients should consume this medicine with caution.
• A person with the history of heat related problems should consume this medicine only by consulting a doctor.
• In case of pediatric patients this medicine should be consumed with extreme caution.

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