Norvasc is an anti-hypertensive medication which contains generic Amlodipine Besylate, which is used in the management of high blood pressure (hypertension). Norvasc is also used to manage coronary artery disease (CAD) in patients without heart failure, and certain kinds of chest pain (angina) from CAD, such as stress and activity induced angina, and in Prinzmetal’s angina (angina occurs at rest angina). You should taken Norvasc regularly to control angina disease, but it doesn't stop chest pain after it has already begun.


This medication belongs to a class of drug calcium channel blockers that blocks the flow of calcium into heart muscles and the muscles along the walls of blood vessels. It selectively blocks L-type channels (one of six kinds of channels in tissues) located in a myocardium, vascular wall, and in cells of conducting and contractile systems of myocardium. Because the contraction of these muscles depends on calcium, Norvasc slow down and enlarges blood vessels, thus improving blood flow and reduces tone of vessels, arterial pressure by stopping Ca+ ions transfer through membrane.
It should not be consumed by those individuals who have oversensitivity to Amlodipine, or have arterial hypotension; it is contraindicated during pregnancy, cardiogenic shock, and nursing mother.


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Dosage regimen of Norvasc tablet:


Norvasc is available in three tablet sizes i.e. 2.5 mg, 5 mg, and 10 mg.


In Adults normally start with a 5 mg dose, with a maximum dose of 10 mg which should be taken via oral route once in a day. It can be taken with diet or in an empty stomach. Adults who are little, weak, old, or have liver problems may be initiated as a 2.5 mg dose of Norvasc tablet.

 

In Children age of 6 to 17 years, the given dose of Norvasc is 2.5 to 5 mg.

 

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In case if you forget to get a tablet, leave out that missed dose completely and consume your next dose at the right time. Do not consume a double dose to catch up for a missed dose.


The most common side effect of Norvasc tablet is edema, or inflammation of the hands, ankles, feet, ankles and lower legs. You are more prone to experience edema with larger doses of Norvasc 5mg, 10mg. Other common side effects of Norvasc which include headache, diarrhea, abdominal pain, nausea, muscle cramps, depression, dizziness, drowsiness, fatigue, flushing, and vomiting.

 

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Precaution and safety points to be followed while using Norvasc 5mg and 10 mg:

 

• Avoid drinking of alcohol as it may enhance the drowsiness effect of this medication.
• Do not drive any vehicle as Amlodipine may affect your alertness and makes you feel dizzy, sick, tired, and headache, speak to your doctor right away.
• This medication should be used with Caution in patients with chronic heart failure diabetes, liver failure, lipid metabolism disorders,
• It should be used with extra care in persons younger than 18 years of old or before consuming this drug you should speak to your doctor.
• Grapefruit and grapefruit juice should not be taken by people who are consuming Amlodipine as grapefruit juice and grapefruit can lead to an enhance in the blood levels of the active component Amlodipine, which can lead to an random raise in the blood pressure reducing effect of this medication.


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